Nasal delivery of high molecular weight drugs. Drug round. Timing of the administration promotes safer medication administration. All the routes of drug administration need to be understood in terms of their implications for the effectiveness of the drug therapy and the patient’s experience of drug treatment. This is usually achieved by oral administration, but other routes are possible. Disadvantages: Holding the dose in the mouth is inconvenient. 0. For example, the site of an injection or any laboratory value or vital sign that needed to be checked before giving the drug. The subcutaneous injection can provide long-term effects of the drug as it has slow adsorption. Advantages and disadvantages of inhaled corticosteroids in the treatment of pulmonary diseases.|2012|Cobanoglu N,|administration &... Search ALLMEDX Now! This method circumvents repetitive injections, prevents delays in analgesic drug administration, and provides continuous levels of pain control without children experiencing increased side effects at peak level and pain breakthroughs at trough levels. March 12, 2017. The most common routes of injection of drugs in small animal practice are iv ,im,ip,sc,ic Usually taken to mean ‘by injection’ Strictly, par-enteral = ‘adjacent the gut’ 15. It therefore allows delivery of smaller drug doses and the occurrence of side effects is reduced compared with systemic routes of drug administration (eg, oral, intravenous and epidural). Inhalers 2. 1,2 By the mid-1970s, the practice of intracardiac injection declined. What are the 7 routes of medication administration? Drug administration via oral routes are very convenient. Routes of administration There are various routes of administration (Box crushed or broken1), each of which has advantages and disadvantages. The values of the plasma area under concentration-time curves (AUC) were similar for both administration routes. Most of the drugs can be administered by different routes. 5. Expensive; Requires trained medical/nursing staff; Irritating drugs may be painful; Slower onset than IV route Routes of Administration of DRUGS By Harshit Jadav 2. Comparative studies of SC versus IV, IM versus IV, or IM versus SC have been sporadically conducted, and some new findings are completely different from the dosage recommendation as described in prescribing information. The principal method of giving drugs is by mouth (oral route), and doses which are not otherwise specified are assumed to be oral doses. use 175 Disadvantages of the I.V. The same drug administered via a certain route 1. may be therapeutic 2. Hence we see anaphylactic shock on giving few drugs and it is difficult to control adverse effects leading to death. Disadvantages of this route: 1. Oral or Enteral Route 3. • Advantages: achieve rapid, precise drug plasma concentration. 2. It has limitations like pain at injection site, lipodystrophy, noncompliance by the patient, etc. - Used if fast onset is required, GI tract is damaged, or the animal is vomiting or has diarrhoea. Otic route. Subcutaneous route of administration is widely preferred method for administration of insulin because of the ease of self-administration. Route # 1. Medical advantages of administering a drug via IV push include a greater systemic concentration of the drug sooner than provided by other delivery routes, administration of a drug when patients cannot take anything by mouth, and reduction of the number and discomfort of intramuscular (IM) injection sites. •Depot preparation (formulation that allow for sustained release of the drug and prolonged action) Intramuscular injection (IM): disadvantages. This method circumvents repetitive injections, prevents delays in analgesic drug administration, and provides continuous levels of pain control without children experiencing increased side effects at peak level and pain breakthroughs at trough levels. Nasal route. Rectal. Box 1. Advantages. Advantages:- 1. Topical or External Application: The drugs administration by this route generally affects to the part to which they are applied. Oily vehicles, drugs that cause hemolysis or precipitation should not be given through this route. Read Also: Intramuscular Route of Drug Administration: Advantages and Disadvantages 1. Bioavailability is 100%. 2. Most addictive route of administration because it hits the brain so quickly Injection. Given that the syllabus-builders have neither infinite time nor infinite paper, some things naturally end up being omitted and routes of administration were one of those things. Subcutaneous or Intramuscular. Parenteral administration. There are several types of routes of administration which are: oral, sublingual, rectal ,tropical, Parenteral – … In a 2015 meta-analysis 4, a literature search was conducted to identify clinical studies published from 1980 to February 2015 that included comparison of IV, IM, or SC administration in order to determine the advantages and disadvantages of each administration route and investigate patient preference. Medical advantages of administering a drug via IV push include a greater systemic concentration of the drug sooner than provided by other delivery routes, administration of a drug when patients cannot take anything by mouth, and reduction of the number and discomfort of intramuscular (IM) injection sites. Intradermal Injection. BP) & titration of the dose with the response is possible. One day in the future it might come up. Here I describe the uses and characteristic adverse effects of commonly used routes of administration. Intradermal injection provides a local and very little systemic effect. Rapid injection of IV medications can have serious consequences for the patient. Simple and Accessible. The major advantage of the subcutaneous route of drug administration is that it is a simple and less expensive method. Vaginal route. At the point when nourishment can’t be taken by mouth, add up to healthful prerequisite can be provided by the parenteral course. The drug is then injected into the spinal canal. ... Major Routes of Drug Administration 13 Terms. Some of the main advantages include: direct access to the circulatory system, a route for administration of drugs and fluids for patients unable to tolerate oral medications and instant drug … The active pharmaceutical ingredients (API) and excipients those have an unpleasant taste and odor are difficult to formulate. Hence we see anaphylactic shock on giving few drugs and it is difficult to control adverse effects leading to death. 50 0 R Where as if given by oral route, the chances of risk are reduced due to digestion or metabolism. Intramuscular injections are much easier to administer. Although it is possible to reverse the actions of some drugs (e.g., opioids, anticholinergics, and benzodiazepines) through the use of specific drug antagonists, this is … What are the advantages and disadvantages of administering medication by injection? The rate of drug absorption is slower than that from intramuscular injection. It is commonly used for tuberculin skin testing but can also be used for allergy testing and local anesthetics. Routes of Drug Administration. These routes need to be Clinical Practice Review Box 1. 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